Strains of Streptococcus pyogenes from Severe Invasive Infections Bind HEp2 and HaCaT Cells More Avidly than Strains from Uncomplicated Infections
نویسندگان
چکیده
منابع مشابه
Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections.
Epidemiologically unrelated Streptococcus pyogenes strains isolated from blood, throat, and skin were assayed for adherence to HEp2 and HaCaT cells. Invasive isolates showed significantly higher avidity for these cell lines than isolates from skin and throat. In general, S. pyogenes showed greater binding to HaCaT cells than to HEp2 cells.
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Objective(s): Streptococcus pyogenes, a notorious human pathogen is responsible to cause a wide range of infections varies from superficial common clinical illness to severe and life threatening infections. To our knowledge this is the first report exploring the emm types and superantigen/exotoxin gene profile of S. pyogenes from Pakistan. Materials a...
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National Institute of Infectious Diseases, Tokyo 162-8640, Tokyo Metropolitan Institute of Public Health, Tokyo 169-0073, Kinki University, Osaka 589-8511, Health Research Institute of the City of Kawasaki, Kawasaki 210-0834, Kanagawa Prefectural Public Health Laboratory, Yokohama 241-0815, St. Marianna University School of Medicine, Kawasaki 216-8511, Ehime Prefectural Institute of Public Heal...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2003
ISSN: 0095-1137
DOI: 10.1128/jcm.41.8.3936-3938.2003